Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GSEAGood_collapsed_to_symbols.cls2class |
| Phenotype | cls2class.cls |
| Upregulated in class | Metastatic |
| GeneSet | AGING |
| Enrichment Score (ES) | 0.6645463 |
| Normalized Enrichment Score (NES) | 1.6530432 |
| Nominal p-value | 0.017857144 |
| FDR q-value | 0.60966015 |
| FWER p-Value | 0.93 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 136 | 1.077 | 0.3263 | Yes |
| 2 | LIMS1 | LIMS1 Entrez, Source | LIM and senescent cell antigen-like domains 1 | 567 | 0.738 | 0.5129 | Yes |
| 3 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 917 | 0.600 | 0.6645 | Yes |
| 4 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 3489 | 0.195 | 0.4434 | No |
| 5 | PDCD4 | PDCD4 Entrez, Source | programmed cell death 4 (neoplastic transformation inhibitor) | 4288 | 0.111 | 0.3909 | No |
| 6 | TBX2 | TBX2 Entrez, Source | T-box 2 | 5254 | 0.010 | 0.2878 | No |
| 7 | KL | KL Entrez, Source | klotho | 6333 | -0.126 | 0.2091 | No |
| 8 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6490 | -0.149 | 0.2391 | No |
| 9 | LOXL2 | LOXL2 Entrez, Source | lysyl oxidase-like 2 | 6500 | -0.150 | 0.2856 | No |
